Prostate Cancer: Prognosis and Life Expectancy for Bone Metastases
Summary of the AJCC 8th stage grouping for prostate cancer with .. these sub- stages may be related to unknown treatment differences rather. What Happens When Prostate Cancer Spreads to the Bones? Having bone metastases will change your treatment options, prognosis, and outlook. spinal cord compression and related weakness or numbness; high blood. Like other forms of cancer, the prognosis for prostate cancer depends cancer commonly spreads to lymph nodes, the bones, liver, or lungs.
These rates compare men with prostate cancer to men in the overall population. But remember, all survival rates are estimates — your outlook can vary based on a number of factors specific to you.
There are a number of limitations to remember: The numbers below are among the most current available. But to get 5-year survival rates, doctors have to look at men who were treated at least 5 years ago.
As treatments are improving over time, men who are now being diagnosed with prostate cancer may have a better outlook than these statistics show.
These statistics are based on the stage of the cancer when it was first diagnosed. The outlook for men with prostate cancer varies by the stage extent of the cancer — in general, the survival rates are higher for men with earlier stage cancers.
The outlook for each man is specific to his circumstances.
Your doctor can tell you how these numbers may apply to you, as he or she is familiar with your particular situation. Survival rates for prostate cancer According to the most recent data, when including all stages of prostate cancer: Given the presence of two versions of AJCC staging system for prostate cancer based on the method of staging i.
Objective The objective is to validate the prognostic value of the changes put forward in the 8th edition of the AJCC staging system in a cohort of patients with clinically staged prostate cancer registered within the SEER database. Selection of the study cohort The SEER database search was limited to the period from — because reliable PSA data were not available before that date.
Prognosis and survival for prostate cancer - Canadian Cancer Society
In order to restrict the inclusion to clinically staged patients, cases with any form of radical surgical treatment to the prostate were excluded. Data collection Data extracted for each record included age at diagnosis, race, T, N and M stages according to the 6th edition6th edition stage group, PSA, Gleason grade, site of distant metastatic disease if applicablecause-specific death classification and survival months.
Through tumor extension information from the collaborative staging section, disease with microscopic bladder neck invasion categorized as T4 in the 6th edition was down-staged to T3a as in 7th and 8th editions. Grade groups were calculated based on the available Gleason scores as follows: Gleason score 8; group 5: Gleason score 9—10 [ 11 ]. In the current study, cancer-specific survival was defined as time from diagnosis to death from prostate cancer.
Survival Rates for Prostate Cancer
Data about performance status of the patients as well as co-morbidity were not recorded in the SEER database. Statistical considerations In this analysis, Kaplan-Meier analysis as well as log-rank testing was used for survival comparisons both cancer-specific and overall survival according to 6th, 7th and 8th editions of the AJCC.
Regarding cancer-specific survival, cases that were alive at the end of the study as well as cases who died of causes other than cancer were censored. Median follow up for the whole cohort is 26 months. Post hoc Bonferroni correction for multiple survival comparisons was not implemented to avoid the risk of exaggerating a type II error in the presence of numerous pair wise comparisons.
- What Happens When Prostate Cancer Spreads to the Bones?